Vitamin K prophylaxis: leaving the old route for the new one?
نویسندگان
چکیده
Oral or parenteral administration of vitamin K is the accepted practice for prevention of early vitamin K deficiency bleeding (VKDB) in the newborn. However, vitamin K prophylaxis in the newborn continues to be a worldwide health concern, particularly in breastfed infants. This paper reviews the current status of the use of vitamin K for the prevention of early and late VKDB.
منابع مشابه
Effects of Vitamins K in Neonates and Young Infants
Vitamin K is required for the hepatic production of blood coagulation factors II, VII, IX and X. The term vitamin K refers to a variety of fat-soluble 2-methyl-1, 4-naphthoquinone derivatives. Vitamin K1 (phylloquinone) occurs in green plants, while vitamin K2 (menaquinone) is synthesized by microbial in the gut. The recommended dose of vitamin K in neonates is 1 mg intramuscularly. For infants...
متن کاملاختلالات انعقادی ناشی از کمبود ویتامین K و ریسک فاکتورهای آن در کودکان تحت درمان آنتی‌بیوتیکی بستری در بیمارستان حضرت رسول اکرم(ص) 1382-1381
Background & Objective: Vitamin K deficiency is one of the commonest causes of coagulopathy and bleeding in patients on prolonged antibiotic therapy. This study was conducted to evaluate the status of vitamin K deficiency in hospitalized children on prolonged antibiotic therapy and its role in reversing the coagulopathy. Method: A prospective non-randomized, cross-sectional study was conduc...
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متن کاملPrevention of Vitamin K Deficiency Bleeding in Newborn Infants: A Position Paper by the ESPGHAN Committee on Nutrition.
Vitamin K deficiency bleeding (VKDB) due to physiologically low vitamin K plasma concentrations is a serious risk for newborn and young infants and can be largely prevented by adequate vitamin K supplementation. The aim of this position paper is to define the condition, describe the prevalence, discuss current prophylaxis practices and outcomes, and to provide recommendations for the prevention...
متن کاملIntracranial hemorrhage associated with vitamin K deficiency in a breastfed infant after intramuscular vitamin K prophylaxis at birth. follow-up at 18 months.
Hemorrhagic disease of the newborn or, more precisely, vitamin K deficiency bleeding (VKDB) in infancy, according to the Committee of the International Society on Thrombosis and Hemostasis (1), is a bleeding disorder due to vitamin K deficiency. It generally occurs during the neonatal period, but it is occasionally seen in infants several months old (2–4). The postnatal administration of vitami...
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ورودعنوان ژورنال:
- Acta paediatrica (Oslo, Norway : 1992). Supplement
دوره 94 449 شماره
صفحات -
تاریخ انتشار 2005